Platelet rich stroma (PRS) treatment knee arthritis Chennai

Osteoarthritis (OA) is a degenerative joint disease that affects millions of people worldwide. It is characterized by the degeneration of cartilage and the underlying bone in a joint, leading to pain, stiffness, and loss of function. The knee is one of the most commonly affected joints in OA, and treatment options for knee OA are limited. However, recent research has focused on the use of stromal vascular fraction (SVF) as a treatment for knee OA.

PRS is a mixture of cells obtained from adipose (fat) tissue. It contains various types of cells, including adipose-derived stem cells (ADSCs), which have the ability to differentiate into various cell types and have the potential to repair and regenerate damaged tissue. At first SVF is obtained via liposuction, which is a minimally invasive procedure. The SVF is then processed to isolate the cells and can be used to treat knee OA. It is then mixed with platelet rich plasma  PRP)  to generate Platelet rich stroma (PRS) which is a powerful combination of regenerative biological products obtained from both fatty tissue and blood

The use of PRS for knee OA is based on the idea that the cells in the SVF can stimulate local resident cells in the joint (cartilage cells)  to repair and replace the damaged cartilage in the knee. Studies have shown that SVF contains a significant number of ADSCs, which have the ability to stimulate chondrocytes and produce cartilage-specific matrix molecules. This suggests that SVF has the potential to repair the damaged cartilage in the knee and improve the symptoms of OA.

Several studies have been conducted to evaluate the efficacy of SVF in the treatment of knee OA. A study published in the Journal of Tissue Engineering and Regenerative Medicine in 2016 found that SVF treatment improved pain and function in patients with knee OA. A randomized, double-blind, placebo-controlled trial published in the same journal in 2017 found that SVF treatment improved pain and function in patients with knee OA and decreased the need for surgery.

Another study published in the Journal of Orthopedic Research in 2019 found that SVF treatment improved pain, function, and quality of life in patients with knee OA. The study also found that the improvement in pain and function was sustained for up to 12 months after treatment.

SVF treatment for knee OA is considered to be a safe and effective treatment option. The procedure is minimally invasive and has minimal risks and complications. However, as with any procedure, there are potential risks such as infection, bleeding, and allergic reactions. It is important to discuss the potential risks and benefits of the procedure with a healthcare provider before deciding to undergo SVF treatment.

In conclusion, Platelet rich stroma ( PRS)  is a promising treatment option for knee osteoarthritis. It is composed of adipose-derived stem cells, which have the potential to differentiate into chondrocytes and produce cartilage-specific matrix molecules and PRP.  Studies have shown that SVF treatment improves pain, function, and quality of life in patients with knee OA. The procedure is considered safe and has minimal risks and complications.